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FBC (Red Cells (HB (High = Polycythemia (Secondary (Sample Error, Hypoxia:…

- - - - MCV
        
        Normal: Normocytic
        
        Acute bleed
        
        Chronicdisease e.g:
        Renal Disease (CKD), Ca
        
        Hemolysis
        
        Large: Macrocytic
        
        Hypothyroidism
        
        Alcohol /liver disease
        
        Pregnacy (very common)
        
        B12/folate deficiency anaemia Further link
        
        Reticulocytosis (immature RBC)
        
        post acute bleed, periods
        
        response to anemia treatment,
        
        CA-marrow infiltration/metastatic cancer
        
        Small: Microcytic
        
        Iron Deficiency Anemia
        
        Check: Ferritin, CRP and Total iron-binding capacity (TIBC)
        
        Chronic Disease
        
        CRP and History
        
        Thalassemia iron deficiency
        
        Genetic blood disorder
        
        lead Poisoning
  - - - Secondary
        
        Sample Error
        
        Hypoxia: Smoking,COPD, Altitude
        
        Erythropoietin due to CA: e.g. Renal cell carcinoma
      - Primary: JAK2 mutation
    - - Now Look at the MCV
- - - - Infection
      - Malignancy
        
        Lymphoma
        
        Leukemia
      - Stress response (fits,trauma) but not overly rasied
    - - Not Producing
        
        Drugs
        
        Melenacy
        
        Fibrosis
      - Destoryed
        
        HIV/Infection
  - - - PARASITIC Infections
    - - Allergies
      - Vasculitis
    - - High: lymphocytosis
        
        VIRAL infections
        
        Leukemia
      - Low: lymphopenia
        
        Steroids
        
        AutoImmune Diseases
    - - High: Neutrophilia
        
        Truma /stress
        
        BACTERIAL infections
        
        Drugs
        
        Malignancy
      - Low: Neutropenic
        
        VIRAL infection
        
        Chemo, some Abx
        
        Splenomegaly
        
        Malignancy