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CNS DRUGS (COCAINE (SIDE EFFECTS (Dizziness, Nausea, Nervousness, Unusual…
CNS DRUGS
COCAINE
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MECHANISM iOF ACTION
inhibit the re-uptake of dopamine after it has been released in the synaptic space. In normal conditions, after being released, dopamine binds with the dopamine receptors of the post-synaptic neuron, activating them and producing a sense of pleasure.
NURSING CONSIDERATIONS
CONTRAINDICATIONS
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Heart disease (e.g., chest pain, heart attack, irregular heartbeat)
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STORAGE CONDITIONS
cold, dry, dark and oxygen-free place
ROUTE OF ADMINISTRATION
snorting, injecting, and smoking
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AMPHETIMINE
NURSING CONSIDERATIONS
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STORAGE CONDITIONS
7-20 hours, protection from light
CONTRAINDICATIONS
Symptomatic CV disease (The heat speeds up),
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CAFFEINE
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MECHANISM OF ACTION
Affects brainstem, spinal cord, and cerebral cortex
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Caffeine, a methylxanthine, is a phosphodiesterase inhibitor. It has an antagonistic effect at central adenosine receptors. It is a CNS and resp stimulant. It has bronchodilating and diuretic properties and it facilitates the performance of muscular work.
NICOTINE
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MECHANISM OF ACTION
Nicotine, a pyridine alkaloid, is a stereo-selective nicotinic-cholinergic receptor agonist. Low doses cause an initial stimulation of autonomic ganglia, adrenal medulla, neuromuscular junction, and brain. High doses produce initial ganglionic stimulation followed by inhibition of neurotransmission leading to subsequent persistent depression of receptor activity.
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