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Anti- obesity drugs (Orlistat (Nursing considerations (Side effects…
Anti- obesity drugs
Orlistat
Mechanism of action
Reduce intestinal fat absorption.
Inhibit pancreatic lipase.
Loss of appetite.
Indications
Reduce body weight gain.
Manage weight loss
Treat high cholesterol.
Nursing considerations
Contraindications
Malabsorption
Pregnancy and breastfeeding.
Reduced gallbladder function.
Hypersensitivity to orlistat.
Anorexia and bulimia.
Side effects
Steatorrhea .
Fecal incontinence.
Acute kidney injury.
Breast cancer.
Colon cancer.
Nausea and vomiting.
Liver failure.
Storage
Away from light
Away from moisture
Keep away from children
Kept in the container
Route of admission
Orally
Sibutramine
Mechanism of action
Inhibits norepinephrine .
Inhibit serotonin.
Inhibit dopamine.
Promote loss of appetite.
Increase energy expenditure .
Nursing considerations
Route of administration
Orally
10mg
Contraindications
Hypersensitivity to sibutramine
History of hypertension.
Anorexia
Taking other anti-obesity drugs
Pregnant women and lactating.
Side effects
Dry mouth.
Headache.
Insomia
Constipation.
Asthemia
Mood chances.
Storage
Protect from light.
Stored in dry place.
15-30 degrees.
Indications
Obesity
Hypertension
Diabetes mellitus.
Rimonabant
Mechanism of action
Cannabinoid CB1 receptor antagonisms
Inverse agonism
Indications
BMI
More than 30kg/M^2
Reduce appetite.
Diabetes mellitus
Type2
Nursing consideration
Side effect
Depressive disorders .
Mood alterations
Nausea.
Upper respiratory tract infection.
Gastroenteritis.
Itchy skin.
Muscle cramps and spasms
Increase falling risks.
Route of admission
Orally.
Storage
Away from light.
Away from children.
Contraindications
Pregnant women.
Allergic to rimonabant
Antidepressants
Seizures.
Hepatic impairment.
Lorcaserin
Mechanism of action
Decrease food consumption
Promote satiety
Activate 5-HT2C receptors
Indications
Increase physical activity
Obesity
High cholesterol
Hepatic impairment.
Renal impairment.
Nursing considerations
Route of admission
Orally
10mg
Side effects
Valvular heart disease.
Hypoglycaemia.
Dry mouth.
Psychiatric disorders.
Cognitive impairment.
Bradycardia.
Pulmonary hypertension.
Contraindication
Pregnancy
Hypersensitivity
Storage
Stored in cool, dry place
Keep away from light.