Please enable JavaScript.
Coggle requires JavaScript to display documents.
Antidiabetic drugs (Sulphonylureas (Nursing considerations (Side effect…
Antidiabetic drugs
Sulphonylureas
Chlorpropamide
Glibenclamide
Gliclazide
Glimepiride
Machanism of action
Lowers blood glucose
Increase insulin production
Increase tissue sensitivity
Indications
Control hyperglycaemia
Lower blood sugar levels
Onset diabetes
Nursing considerations
Contraindications
Type1 diabetes
Pregnancy and lactation .
Severe renal failure.
Hypersensitivity to sulphonyluereas :
Side effect
Nausea and vomiting.
Severe diarrhea .
Confusion.
Bradycardia
Vision loss.
Sweating.
Severe dizzness
Route of Administration
Orally.
Storage
Keep in container
Tightly closed
Room temperature
Away from sunlight
Away from moisture
Insulin
Mechanism of action
Insulin binds to a insulin receptor on cell membrane
Cell response is triggered
Glucose and other sugers are transported away from the blood
Glucose is transported into other cells
Insulin increase activity of glucose transporters
indications
diabetes
Diabetic kitoacidosis
Hyperglycemia
High blood potassium levels.
Hyperosmolar hyperglycemic
Nursing considerations
Contraindications
Hypoglycemia
Allergic reactions
anaphylaxis
Hypokalemia
Liver problems
Kidney disease
Side effect
Weight gain.
Swelling of arms and feet.
Swelling around injection site.
Hypoglycemia
Skin changes at site.
Rash
Itching.
Bumps
Sweating
Dizzness
Storage conditions
Room temperature
15-25 degrees
28 days
refridgeted
2-8 degrees
Route of administration
Intravenously .
Subcutanously.
Metformin
Mechanism of action
Reduce glucose absorption
From the gastrointestinal tract
Stimulate uptake of glucose into muscle
Inhibit gluconeogenesis
Reduce reliese of glucose
From the liver
Indications
Prevent kidney damage.
Prevent blindness.
Nerve problems .
Loss of limbs .
Sexual function problems.
Increase muscle sensitivity.
Nursing considerations
Contraindications
Acute myocardial infaction
Severe heart failure
Renal impairment
Side effect
Nausea and vomiting .
Diarrhea.
Weight loss.
Upper respiratory tract infection.
Abdominal pain.
Hypoglyceamia
Weakness
Storage
Keep in container
Tightly closed.
Room temperature
Away from light
Moisture
Route of administration
Orally)
Thiazolidinediones
Mechanism of action
Reduce tissue resistance to insulin.
Increase insulin sensitivity
Indications
Treat Type2 diabetes.
Nursing consideration
Contraindications
Pregnancy
Breast feeding
Liver disease .
History of heart failure
Not taken with insulin
Side effect
oedema.
Weight gain.
Heart failure.
Bone fracture.
Storage
Room temperature
Route of Administration
Orally