otic drug (antipyrine benzocaine (side effect (CNS: headache, restlessness…
mechanism of action
local anaesthetics work by causing a temporary interruption in the production and conduction of nerve impulses.
they effectthe permeability of nerve membranes for sodium ions, by preventing the sodium ions from entering the nerve. they stop the nerve from depolarizing.
reduce the height and rate of rise of action potential and increase the excitation threshold. conducting velocity is slowed too.
local anesthetics are broken down immediately in the plasma by enzyes called plasma esterses.
infiltration anesthesia, peripheral and sympathetic nerve blocks, central nerve block, spinal cord cavidal anesthesia topical anesthetic for skin disorder.
children: support and reassurance for any skin breakdown related to immobility
adult: health education base on what will happen during administration of benzocaine
allegery: to avoid hypersensitivity reaction.
heart block, could be exarcebated with systemic absorption.
shock, can alter local delivery and absorption of these drugs
pregnancy, lactation: potential adverse effect to fetus and baby
CNS: headache, restlessness, anxiety, dizziness, blurred vision, backach.
CV: peripheral vasodilation, myocardial,deppression
GI: naysea, vomiting
loss of skin intergrity
store in a cool dry place.
away from heat
out of reach in children
route of administration
topical: involves the application of cream, lotion, ointment of local anesthetic to traumatized skin to relieve pain.
bacterial infection of middle ear and
hole in the ear drum
mechanism of action
they are employed for their analgesic anesthetic effect. the anhydrous glycerin vehicle is hygroscopic and may provide a decongestant action.
antipoyrine has been used to relieve pain and inflammation in the congestive and serous stages of acute otitis media and to facilitate removal of cerum from the wall of the ear canal
route of administration.
store in a cool place way frm heat. do not freeze
burning, stinging, redness, new pain in or around the ear. bluish skin, severe tiredness, hearing loss. rash, itching,swelling(especially of the face, tongue and throat) severe dizziness, trouble breathing.
antipyrine benzocaine glycerin