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Liver tumors (Malignant (Cholangiocarcinoma
(bile duct CA) (Anywhere in…
Liver tumors
Malignant
Angiosarcoma
Endothelial origin
• Factor VIII, CD34(+), CD31(+)
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A/w: Thoroclast, arsenic, vinyl chloride
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Hepatocellular carcinoma
90% primary hepatic malignancies
• Uncommon in US & Europe
• :red_flag::<3:red_flag:MC visceral malignant tumor in males
Associations:
• Hep B & C
• Aflatoxin (beans)
• Causes of cirrhosis (hemochromatosis, EtOH, AAT deficiency, NAFLD)
Histology varies
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Fibrolamellar HCC
• From normal liver instead of cirrhotic one
• Adolescents & young adults
• Better prognosis
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Benign
Hepatic adenoma
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Pathology
• Solitary
• Central hemorrhage & necrosis
• :star:Absent lobular pattern (no portal tracts or central veins)
• Normal hepatocytes, though
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