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Hazardous and Toxic Agents in Animals (category (Toxic chemicals (mutagens…
Hazardous and Toxic Agents in Animals
category
Infectious diseases
CDC/NIH publication: Biosafety in Microbiological and Biomedical Laboratories,
BMBL:guidelines for working with a wide variety of infectious agents in both research laboratories and the animal facility.
4 levels
Biosafety Level 2
agents that pose moderate hazards to personnel and the environmen
access to the laboratory is restricted when work is being conducted
Biosafety Level 3
indigenous or exotic agents that may cause serious or potentially lethal disease through inhalation route exposure
Laboratory personnel must receive specific training in handling pathogenic and potentially lethal agents and must be supervised by scientists competent in handling infectious agents and associated procedures.
Biosafety Level 1
well-characterized agents not known to consistently cause disease in immunocompetent adult human
not necessarily separated from the general traffic patterns in the building. Work is typically conducted on open bench tops using standard microbiological practices
Biosafety Level 4
Access to the laboratory is controlled by the laboratory supervisor in accordance with institutional policies
dangerous and exotic agents that pose a high individual risk of life-threatening disease, aerosol transmission, or related agent with unknown risk of transmission
The Biosafety Level 4 laboratory has special engineering and design features to prevent microorganisms from being disseminated into the environment.
A Cabinet Laboratory where all handling of agents must be performed in a Class III BSC
A Suit Laboratory where personnel must wear a positive pressure protective suit.
Toxic chemicals
mutagens
biological toxins
organic chemicals
carcinogens
Radioactive substances
Recombinant DNA