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Immunology 4 - infection + immunity - how organisms evade the immune…
Immunology 4 - infection + immunity - how organisms evade the immune system + assessment of immune function (ii)
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Immunodeficiency
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T cell defect
infections with viral , fungal + protozoal pathogens
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B cell defect
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primary causes = x-linked hypogammaglobulinaemia, common variable immunodeficiency (CVID)
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Spleen
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filters blood (removes abnormal particles - old/abnormal RBCs, pathogens incl parasites such as malaria, immune complexes
hyposplenism
causes
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coeliacs (small assymptomatic splenic infarcts, not reversed by gluten-free diet)
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