Wong_Melinda_Block4_MM9

Mendel Law of Inheritance

Law of Segregation

Law of Assortment

Paired set of alleles for a gene will separate into 2 different gametes

alleles for different genes sort independently of each other

Exceptions

Unlinked genes always sort independently

linked only sort independently if there's a crossover

Mendel's Experiment

P Generation

true-breeders

F1 Generation

hybrids

F2 Generation

offspring of F1 generation

parents of F1 cross

Shows dominant phenotype

homozygous dominant or homozygous recessive

One dominant allele and one recessive allele

Phenotype all dominant ratio 4:0 (monohybrid)

different phenotype

3:1 ratio for phenotype (monohybrid)

1:2:1 ratio for genotype (monohybrid)

genotype ratio 0:4:0 (monohybrid)

Product of F2 Cross

Product of F1 cross

Dihybrid Cross

F2 Generation

Phenotype ratio 9:3:3:1

observing 2 genes

Test Cross

cross individual w/ dominant phenotype w/ individual w/ dominant recessive

if there are phenotype with recessive phenotype then parent is heterozygous

if there are no phenotype with recessive phenotype then parent is homozygous dominant

Probability Rules

Product Rule

p(A×B) = p(A) × p(B)

Sum Rule

p(A+B) = p(A) + p(B)

And

Or

Codominance

Incomplete dominance

Red x White = Pink

Red x White = Red & White

Chromosome Disjunction

2n+1

2n-1

X-chromosome inactivation

looks like codominance

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