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Communication, Integration, Homeostasis (Local Communication (Gap Junction…

- - - - ligand bind to proteins
        
        Rule for protein bind to chemical signal
        
        affinity
        
        competition
        
        specificity
        
        saturation
- - - - reach target cell by diffusing through interstitial fluid
- - - - hormones target cell only
  - - - use electrical and chemical signal
        
        electrical
        
        signal travel nerve/neuron cell
        
        chemical
        
        secreted by neuron
        
        neurocrine molecules
        
        neurocrine act more slowly as autocrine or paracrine
        
        call neuromodulator (slow)
        
        neurocrine molecule diffuse into blood
        
        neurohormones
- - - - bind cytosolic receptor or nuclear receptor
        
        intracellular receptor activated and turn on gene and make new mRNA
        
        process slow
      - hormones
  - - - bind to receptor protein in cell membrane
- - - - activates receptor
        
        receptor in turn activates one or more intracellular signal molecules and to target cell
        
        creates a response by existing or initiating protein