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TYPES OF LIVER DISEASE (Congenital (Inherited metabolic conditions…
TYPES OF LIVER DISEASE
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Acquired
Hepatocellular disease
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Cirrhosis = long-term damage (irreversible)
inflammation + necrosis → fibrosis
→ jaundice, ascites, portal HTN, sig. dysfunction
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Neoplasia
- Hepatocellular carcinoma*
- Cholangiocarcinoma
- Angiosarcoma
- Metastatic deposits
Fatty Liver - associated w obesity, metabolic synd, T2DM
- Non-alcoholic fatty liver (no sig. inflamm'n or scarring)
- Non-alcoholic steatohepatitis (FL + inflmmation, scarring)
Extrahepatic biliary obstruction
- Gallstones
- Pancreatic carcinoma
- Biliary atresia
Haemolysis
- Malaria
- Yellow fever
- Sickle cell disease
- Incompatible transfusion
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