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Cell-Cell-Junctions (Tight-Junctions (Struktur (Claudin (essentiell),…
Cell-Cell-Junctions
a) Sealing Function
nicht absolut (kl. Moleküle, Ionen)
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a) Adherens Junction
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Assembly:
- Protrusions --> Cell-Cell Kontakt
- Cadherine & Catenine Clustern
- Recruitment mehr Aktinprotrusions (Rac), Cadherin, Catenin
- Ausbildung Aktin-Myosin (Rho)
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b) Desmosome
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für Zellen mit hohem mechan. Stress (Epidermis, Herzmuskel)
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