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Depressive disorders (population subgroups (men may tend to show tiredness…

- - - - major depressive disorder
        
        lowered mood most of the time, most days
        
        reduced interest or pleasure in most activities
        
        significant weight loss or weight gain
        
        daily insomnia or hypersomnia
        
        reduced or agitated motor activity
        
        fatigue or loss of energy
        
        feelings of worthlessness or inappropriate guilt
        
        diminished concentration and cognition
        
        recurrent thoughts of death, suicidal ideation, suicidal plan.
    - - Recurrent depressive disorder
        
        repeated episodes of depression without any history of mania (increased energy)
        
        lowered mood, varying little and unresponsive to changing circumstances
        
        reduced energy, decreased activity
        
        tiredness after minimum effort
        
        reduced enjoyment, interest, pleasurable feelings, concentration
        
        sleep disturbances
        
        reduced self-esteem and self-confidence
        
        ideas of guilt and worthlessness
        
        slower motor activity, loss of appetite and libido, weight losss
    - - Mild: two or three symptoms; patient is able to continue most activities despite distress
      - Moderate: four or more symptoms; great difficulty continuing normal activities.
      - Severe (without psychotic symptoms): several symptoms are distressing, especially loss of self-esteem and ideation of worthlessness; somatic or bodily symptoms are typically present.
    - - DSM-5
        
        At least 2 weeks, though most episodes last longer
      - ICD-10:
        
        Each episode varies from a few weeks to a few months
    - - At any age from childhood to old age; average age of onset is in the mid-20s; age of onset is younger for those more recently born.