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The effects of burns on the renal and digestive systems (Digestive system,…
The effects of burns on the renal and digestive systems
Renal system
Hypovolemia
Extra-vascular fluid loss
Decreased renal blood flow & glomerular filtration rate
Results in ischemia & cell death
Decreased cardiac output
Stress hormone (Angiotensin, Vasopressin, Aldosterone)
Denatured proteins
Rhabdomyolysis release of myoglobin into systemic circulation
Blockage of renal tubules
Constriction of afferent arterioles
Generation of oxygen free radical
Injures the renal tubular cells
Renal insufficiency
Digestive system
Paralytic ileus
Cause intestinal infections (gastroenteritis)
Decrease in mucus production by the stomach
Gastrointestinal tract bleeding
Curling's Ulcer (Stress Ulcer)
Reduced plasma volume
Cause ischemia & cell necrosis of the gastric mucosa
Mucosal atrophy
Decreased absorption & increased intestinal permeability
Increased bacterial translocation
Septicemia
Increasing intra-abdominal pressure (IAP)
Reduced blood flow to the abdominal
Cause Abdominal Compartment Syndrome (ACS) & Intra-abdominal hypertension (IAH)