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Chronic Inflammation (Granuloma (Epithelioid histiocytes (Large nuclei,…
Chronic Inflammation
Granuloma
Granulomatous disease includes TB, leprosy + Crohn's
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Microscopic Features
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Macrophages, some may form multinucleate giant cells. They contribute to necrosis
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Causes
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Primary chronic inflammation (no initial acute inflammation):
Autoimmune disease
TB, leprosy, viral infections
Uric acid crystals
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DEFINITION
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Cells involved in chronic inflammation:
Plasma cells
Lymphocytes
Macrophages
Fibroblasts
Capillary endothelium
Multinucleate giant cell
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