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((• Acid – base balance & Fluid Homeostasis (o Fluid…
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o Changes in blood PH & health effects (systems, tissues)
• Starvation, injury and sepsis: Immunological & Metabolic response
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• Microbiome, the gut and the blood brain barrier
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o Insulin resistance, metabolic syndrome, T2D
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• Metabolic hormones, vascular function and ageing (Matthew Gage)
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o HCY metabolism – Vit B6, folic acid
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o (sodium, protein, energy etc.); exercise advice
• Alcohol, liver disease and nutrition
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• Nutrition, intestine & liver
o Aetiology of Crohn’s disease, Pancreatic insufficiency, Liver failure
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o Intestinal, pancreatic and liver failure have profound nutritional effects and may co-exist
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o Explain that tumorigenesis results from accumulation of random mutations producing selective advantages.
o Hallmarks of cancer and explain how these represent essential selective advantages for tumorigenesis
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