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Diagnosis of pregnancy (Clinical
presentation (Urinary frequency
Inc…
Diagnosis of pregnancy
Clinical
presentation
Urinary frequency
Inc plasma vol and urine production,
bladder pressure from uterus
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Nausea and vomiting
1st trimester, but may persist
Any time of day
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Investigations
Pregnancy test
Timeframe
Generally detect from first week of missed period
Earliest: +ve from Day 9 conception (Day 23/28)
Latest: 20 weeks
Miscarriage/foetal death: stay +ve 5d
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Physiology
HCG secreted from trophoblastic tissue
Massive increase Day 8 after ovulation, peaks 8-12wk
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