The Eye and The Endocrine System Christina Gatica, Period 1

Major structures and functions of the Eye

Major functions of the Endocrine System

Major glands and organs and their functions

Name of hormone and their target organs and functions

Hypothalamus

Glands

Organs

Pituitary Gland

Pineal Gland

Thyroid Gland

Parathyroid Gland

Adrenal Gland

Pancreas

Gonads

Thymus

non-glandular organs

Heart

Kidneys

Digestive System

Adipose

Placenta

Anterior Pituitary

Posterior Pituitary

Thyroid Gland

Parathyroid Gland

Adrenal Cortex

Adrenal Medulla

Pancreas (Islets)

Testes

Ovaries

Thymus

Pineal Gland

diseases associated with the endocrine system

Melatonin hormone: target is the brain tissue

Function: Helps regulate the human sleep-rate

Estrogen hormone: target are the muscles

Progesterone hormone: target are the uter glands

Function: function as the primary female sex hormones

Function: most active in females during ovulation and pregnancy where it maintains appropriate conditions int he human body to support a developing fetus.

Insulin hormone: target is the blood

Function: produced by alpha cells which is responsible for raising blood glucose levels

Glucagon hormone: target are the muscle and liver cells

Function: produced by alpha cells responsible for raising blood glucose levels.

Cortisol (glucocorticoids) hormones: target are the inflammation lipids

Function: breakdown of proteins and lipids to produce glucose.

reduces inflammation and immune response

Aldosterone (mineralocorticoids) hormone: target the kidneys

Function: help regulate the concentration of mineral ions int he body

Parathyroid Hormone (PTH) : target the osteocytes

Function: helps with calcium ion homeostasis occurs when calcium levels in the blood drop below a set point.

Antidiuretic Hormone (ADH): targets the kidneys

Function: prevents water loss in the body by increasing the re-uptake of water in the kidneys and reducing blood flow to sweat glands.

Oxytocin hormone: targets the uterus and the breasts

Function: triggers uterine contractions during childbirth and the release of milk during breastfeeding.

Growth Hormone (GH): targets the target cells

affects many target cells throughout the body by stimulating their growth, repair, and reproduction.

Thyroid-Stimulating Hormone (TSH): targets the thyroid gland

a tropic hormone responsible for the stimulation of the thyroid gland.

Adrenocorticotropic Hormone (ACTH): targets the adrenal cortex

stimulates the adrenal cortex, the outer part of the adrenal gland, to produce its hormone.

Prolactin (PRL): targets memmary glands

stimulates the mammary glands of the breast to produce milk

Follicle-stimulating Hormone (FSH): targets the follice cells

stimulates the follicle cells of the gonads to produce gametes in females and sperm in males.

Luteinizing Hormone (LH): targets the glands

stimulates the gonads to produce the sex hormones estrogen in females and testosterone in males.

Epinephrine/ Norepinephrine hormone: targets the blood flow

helps increase the flow of the blood to the brain and muscles to improve the fight or flight response to stress.

Thyroid Hormone: targets metabolism

regulates metabolic rate

Calcitonin: targets the calcium bons

reduce the concentration of calcium lens in the blood.

testosterone: targets the muscles and liver cells

regulate the growth and activity of cells that are receptive to male hormones

In adult males androgen are produced more by the testis which leads to appearance of male secondary sex characteristics.

Thymosin: targets the T-Cells and the blood

help to train and develop t-lymphocytes during fetal development and childhood.

Inactive during puberty ad slowly replaced by adipose tissue

Adrenal Cortex

Adrenal medulla

produces many cortical hormones in 3 classes; glucocorticioids, mineralocorticoids, and androgens

Glucocorticioids: break down proteins and lipids to produce glucose. Also function to reduce inflammation and immune response

Mineralocorticoids: group of hormones that help to regulate the concentration of mineral ions in the body

Androgens: produced at low levels in the adrenal cortex to regulate the growth and activity of cells that are receptive to male hormones

produces the hormones epinephrine and nor epinephrine under stimulation by the sympathetic division of the autonomic nervous system.

They help release the flow of blood to the brain and muscles to improve the fight or flight response to stress.

produces three major hormones: Calcitonin, Triiodothyronine, Thyroxine

Calcitonin is released when calcium ion levels in the blood rise above a certain set point.

Anterior Pituitary

Posterior Pituitary

Oxytocin triggers uterine contractions during childbirth and the release of milk during breastfeeding

Antidiuretic hormone (ADH) prevents water loss in the body by increasing the re-uptake of water in the kidneys and reducing blood flow to sweat glands.

produces 6 important hormones

The function of the anterior pituitary gland is controlled by the releasing and inhibiting hormones of the hypothalamus

Thyroid stimulating hormone, adrenocorticotropic, follicle stimulating hormone, Luteinizing hormone, human growth hormone, Prolactin hormone

small pinecone-shaped mass of glandular tissue found just posterior to the thalamus of the brain.

the activity of the pineal gland is inhibited by stimulation from the photoreceptors of the retina.

Increased melatonin production causes humans to feel drowsy at nighttime when the pineal gland is active

produces 3 major hormones

Calcitonin, Triiodothyronine, and thyroxine

the pancreas is considered to be a heterocrine gland as it contains both endocrine and exocrine tissue.

The alpha cells produce the hormone glucagon, which is responsible for raising blood glucose levels. Glucagon triggers muscle and liver cells to break down the polysaccharide glycogen to release glucose into the bloodstream.

The beta cells produce the hormone insulin, which is responsible for lowering blood glucose levels after a meal

These sex hormones determine the secondary sex characteristics of adult females and adult males.

Testes: This hormone causes growth and increases in strength of the bones and muscles, including the accelerated growth of long bones during adolescence

The thymus produces hormones called thymosins that help to train and develop T-lymphocytes during fetal development and childhood

The thymus becomes inactive during puberty and is slowly replaced by adipose tissue throughout a person’s life.

capable of producing the hormone atrial natriuretic peptide (ANP) in response to high blood pressure levels.

ANP also reduces blood volume and pressure by causing water and salt to be excreted out of the blood by the kidneys.

produce the hormone erythropoietin (EPO) in response to low levels of oxygen in the blood

The hormones cholecystokinin (CCK), secretin, and gastrin are all produced by the organs of the gastrointestinal tract

produces the hormone leptin that is involved in the management of appetite and energy usage by the body. Leptin is produced at levels relative to the amount of adipose tissue in the body, allowing the brain to monitor the body’s energy storage condition

In pregnant women, the placenta produces several hormones that help to maintain pregnancy

also prevents premature delivery of the fetus

responsible for the direct control of the endocrine system through the pituitary gland

The hypothalamus contains special cells called neurosecretory cells—neurons that secrete hormones

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Thyrotropin-releasing hormone (TRH)

Growth hormone-releasing hormone (GHRH)

Growth hormone-inhibiting hormone (GHIH)

Gonadotropin-releasing hormone (GnRH)

Corticotropin-releasing hormone (CRH)

Oxytocin

Antidiuretic hormone (ADH)

Sclera

pupil

Iris

Cornea

Lens

Retina

Conjuctiva

extrinsic eye muscles

Choroid

Ciliary Body

prevents light scatter within the eye

lines the surface of the eyelid, and secretes mucous that lubricates the eyeball

allows light to be properly focused

regulates amount of light entering the eye

protects and shapes the eyeball

opening which through light passes

allows light to enter the light

contains photo receptors that convert light

controls eye movement

controls lens shape

Optic nerve

transmits visual information from the eye to the brain

Optic disk

the blind spot; where the optic nerve leaves the eye

aqueous humor

maintain intraocular pressure of the eye

vitreous humor

provides major internal reinforcement of the posterior part of the eye.

Thyroid disease

Osteoporosis

abnormal production of thyroid hormones

bone disease that occurs when the body loses too much bone, makes too little bone, or both

Adrenal gland disorder

Cushing's syndrome, there's too much cortisol, while with Addison's disease, there is too little. Some people are born unable to make enough cortisol