Please enable JavaScript.

Coggle requires JavaScript to display documents.

Head & Neck Pathology (Oral cavity (:star: Squamous cell carcinoma…

- - - - Lateral border of tongue
      - • Shaggy parakeratosis
        • Vacuolated epithelial cells (balloon cells)
      - • Caused by EBV
        • In HIV/AIDS patients
    - - Causes (also RFs for SCC):
        • Tobacco
        • Alcohol
        • Irritation (ill-fitting dentures, bad oral hygiene)
      - Males, 40-70 y/o
      - Can't scrape off
      - Keratosis
      - Pre-malignant potential
    - - Easily scraped off
  - - - Gross: Hard & irregular +/- bleeding
      - Micro: Keratin pearls and whorls
      - Local invasion --> Met to lymph nodes --> Neck mass --> 50% distant/systemic met in lung, liver, bones
- - - - Pseudocyst (no epithelial lining)
        • Mucin cysts lined by inflammatory granulation tissue
      - Trauma --> Common in lower lip & buccal mucosa
    - - • Epithelial & stromal (cartilage)
        • Gray-white, myxoid.
      - MC salivary gland tumor
        F > M
      - :!:MC: Superficial lobe of parotid
        • Painless, slow-growing mass at pre-auricular area/jaw angle
      - Tx: Excise! High recurrence though.
      - Can become "carcinoma ex-pleomorphic adenoma"
        • CN7 involvement
    - - 2nd MC salivary tumor
        M > F
      - Parotid!
      - Cystic spaces surrounded by lymphoid tissue
  - - - Origin: Ductal epithelium
        Squamous + Mucinous cells
        • Low-grade: More mucus cells, less squamous
        • High-grade: More squamous, less mucus
      - 60-70% from parotid (CN7 involvement)
      - F > M
      - Slow-growing, painless, firm mass
    - - Slow-growing
        Invades locally and recurs after resection
      - 20% of minor salivary gland tumors
- - - - Cervical lymph nodes (neck mass)
      - Chronic otitis media
        (Eustachian tube block)
- - - - 2/3 laryngeal CA's
      - TRUE vocal cords
      - Slow metastasis. Good prognosis