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Disease (work on SCA12 and PPP2R2B (genetics, Role of two protien isoforms…
Disease
- work on SCA12 and PPP2R2B
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- what is lacking in the history and should be studied
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who is the actual culprit: CAG at RNA levels, RNA expression levels, protein expression
RNA-FISH using probes against PPP2R2B that is supposed to target all the transcript isoforms along with probes targeting
- what is the disease, what makes this disease unique and worth studying
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- highlighting the disease prevalence and disease symptoms
- how do clinicians and scientists diagnose it
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- Background on which hypothesis is built(DEEPAK SIR'S AND FXTAS STUDIES)
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- how my work will impact the treatment for SCA12