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Acute Asthma Exacerbation (Pathophysiology (oxidant stress increase immune…
Acute Asthma Exacerbation
Pathophysiology
oxidant stress increase immune response
airway swells & produce extra mucus
increase resistant airways
bronchial tubes quickly narrow
severe inflammation & exaggerated immune response
dendrite cell detection
antigen/allergen
onset of life-threatening symptoms
Treatment
Rescue Medication
oral corticosteroids
epinephrine pen
atrovent
short acting beta agonists
Diagnosis
peak flow
arterial blood gas
present signs & symtoms
spirometry
nitric oxide measurement
Clinical Presentation
anxiety or panic
none stop coughing
chest pain
retractions
severe shortness of breath
severe wheezing
rapid breathing
increased heart rate
Epidemology
females higher rate exacerbation
females increase severity exacerbation
virus
African Americans & Puerto Ricans asthma severity higher
genetics
Exacerbation Triggers
pet hair & danger
mold/dust
cigarette smoke
cold air
allergen exposure
stress/physical activity