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Acute Asthma (Pathophysiology (Inflammatory response activation, T-Cell…
Acute Asthma
Pathophysiology
Inflammatory response activation
T-Cell Activation
Eosinophil production
Mast cell activation
Epithelial cell injury
Increased Mucus secretion
Airway Inflammation- causing hyperresponsiveness & airflow constriction
Epidemiology
7 Million children diagnosed
34 Million Americans affected
5-7% of the population affected
Blacks suffer from higher morbidity & mortality
During childhood: 2:1 male to female ratio
Adulthood: 1:1 male to female ratio
Clinical Presentation
Airway narrowing
Coughing
Wheezing
Dyspnea & Chest tightness
Hypoxemia & respiratory alkalosis
Hyperventilation
Diagnosis
ABGs
Pulmonary Function Test
Chest Xray
Pulse Oximetry
Treatment
Oxygen Adminstration
Bronchodilators
Corticosteroids