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thyroid (carcinoma (FC (RAS (1/2), tt(PAX8-PPAR-Y1) in 1/3, loss of PTEN)…
thyroid
carcinoma
FC
RAS (1/2)
tt(PAX8-PPAR-Y1) in 1/3
loss of PTEN
MC
in younger (familial +MEN SYNDROME )
RET
PC
RET in (ch10q11)
ret/PTC => inc (RET +MAP ) IN 1/5
BRAF => inc MAP (1/3 - 1/2 )
AC
RAS
PIK3CA
both of them leed to :no_entry: P53
adenomas
PIK3CA
PPAR-G
PAX8
RAS