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SPECT VS. PET (SENSIVITY (SPECT(Low) (Physical Half-life (3-4 hours),…
SPECT VS. PET
SENSIVITY
SPECT(Low)
Physical Half-life (3-4 hours)
shorter collimator - to reject smaller portion of incident event
PET(High)
PHYSICAL HALF LIFE
SHORT (76 s) / Rb-82
SPATIAL RESOLUTION
PET
PHOTON NO-COLINEARITY
e+ and e- annihilates 180 degree
POSITRON RANGE
Travel before reach thermal energy
DETECTOR RELATED
weak of scintillation crystal
inter-crystal scattering
inter-crystal penetration
SPECT
SEPTAL SCATTER
Photon Scatter in Collimator septa
Photon remain in detector window
INTRINSIC RESPONSE
Noise in signal output PMT
Scattering
GEOMETRIC RESPONSE
Distance Collimator
Collimator Design
SEPTAL PENETRATION
Penetration at septa
TEMPORAL RESOLUTION
PET
use 5D reconstruction algorithm
each voxel represented continuously over the time
TR increase - higher sensitivity : ability to acquire shorter frame
SPECT
4D Reconstruction algoritm( each voxel conform to complementary model)
slow image acquisition