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Deep Vein Thrombosis DVT (Treatment (IV anti-coagulation therapy…
Deep Vein Thrombosis
Epidemiology
Triad of Virchow
Veinous Stasis
Immobility
Age
Congestive Heart Failure
Venous Entothelial Damage
Trauma
IV Medications
Hyper-Coagulative States
Inherited disorders
Malignancy
Pregnancy
Oral Contraceptives
Hormone Replacement Therapy
Pathophysiology
Accumulation of:
Platelets
Clotting Factors
Near venous valve
Leads to:
blood clot formation
Inflammation around the clot
Increase in platelets
Growth of blood clot
Increased pressure behind clot leads to edema
Clinical Presentation
Usually asymptomatic
Can be associated:
Pain
Edema
Diagnosis
Serum D-dimer measurement
Doppler ultrasonography
Treatment
IV anti-coagulation therapy
Heparin
Warfarin
Oral anti-coagulation therapry
Xa inhibitors
Direct thrombin inhibitors
Thrombolytic Therapy
Placement of inferior vena cava filter
