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Gastric cancer (Risk factors (Smoking, Alcohol, H pylori, Diet High salt …

- - - - Radiotherapy
        Indication: neoadj for surgery, palliative
        MOA: alone or chemo-RT
      - Chemotherapy
        Indication: neoadj for surgery, met disease
        E.g. cisplatin, flurouracil
        MOA: alone or chemo-RT
      - Immune therapy
        Indication: HER2+ metastatic gastric cancers
        E.g. trastuzumab
    - - Resection
        Indication: local disease
        MOA: endoscopic mucosal resection (superficial)
        gastrectomy (invasive; total/subtotal, Roun en Y reconstruction)
        Complications: bleeding, anastomotic leak, dumping syndrome, anaemia (Fe, folate, B12 [intrinsic factor]), impaired fat absorption, reflux gastritis, osteoporosis/osteomalacia
      - Stenting
        Indication: palliative for extensive disease
        MOA: bypasses stricture for symptom relief