Alzheimer's Disease-Early symptoms are forgetfulness, disorientation, and difficulty with concentration, calculation, language and judgement. As disease progresses, patients can have severe behavioural disturbances and may become psychotic. In final stages, individual becomes bed-bound and needs carers. Reductions in acetylcholine, somatostatin, monoamines and glutamate. These neural systems normally are responsible for attention, memory, learning and higher cognitive abilities cause the clinical symptoms