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(Physiology (Excrete UnAbs Drug @ end of GI Transit, pH, Transit Time, C1 …
Physiology
Excrete UnAbs Drug @ end of GI Transit
pH
Transit Time
C1 - C4
ASF Model
Qh (L/Min)
% Fluid in SI
% Fluid in Colon
Zero order Gastric Emptying
Compound
Transporter
Precipitation Time
Diffusion Coefficient
Drug Particle Density
Permeability
Enzyme
Pharmacokinetics
Blood:Plasma Ratio
Plasma Fup
CL
Vc
Body Weight
Renal Clearance
Inputs
pH Solubility Profile
pH Degradation Profile
IV Data
In Vitro Dissolution [IR]
In Vitro Dissolution [MR]
Oral Data
Simulation Seup
Dissolution Model
Precipitation Model
Permeability Model
Enterohepatic Circulation