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Virology (Structure (Naked: (Easier spread, Rota/norovirus, Stable in…
Virology
Structure
obligate intracellular parasites, depend on biochemical machinery.
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Icosahedron (20 sides), filament etc.
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Enveloped (HIV, Ebola, Inf).
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Infection
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Assembled in nucleus, lysis release.
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Few drugs, high mutation, easy spread, latent and persistant
Lifecycle- Retrovirus
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Neg. sense ss RNA (flu, MMR, Ebola)
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Caspid proteins, replication
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Pos. sense ss or ds RNA:
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Polio, dengue fever, hep C
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mRNA (subgenomic), Replication