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Chapter 5 (5-1 Describe the main structural features of the epidermis, and…
Chapter 5
5-1 Describe the main structural features of the epidermis, and explain their functional significance
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Stratum Basale- innermost layer. directly above basement membrane, composed of single row mitosing cuboidal epithelial cells and composed of melanocytes
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Stratum Lucidum-translucent layer cells separating, extra layer in thick skin
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Pigment=Melanin
determines skin color, produced by melanocytes in stratum basale
Skin Functions
Physical Barrier
pH or 5-6, prevents microorganism growth
Chemical Barrier
Langerhan’s cell (epidermis), Macrphages and mast cells (dermis)
Biological Barrier
From water loss, from injury, from chemical and microorganisms
Cutaneous Sensation
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Pressure detection
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Vitamin D synthesis
UV rays in sunlight activate its synthesis, Vitamin D is required for bone homeostasis
Blood Reservoir
The dermis houses about 10% of the body's blood vessels, Skin only requires 1-2% of the body's blood
Immunity
Langerhan's cells (macrophages), interact with T-helper cells in immune responses
Skin and its tissues
Epidermis-Outermost layer, keratinized stratified squamous ET
Dermis-inner layer, keratinized epithelium, glandular epithelium, dense irregular CT, smooth muscle tissue, nervous tissue, blood vessels
Subcutaneous layer- adipose tissue, distinct layer beneath skin, “hypodermis”
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5-7 Various Glands
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Merocrine
Coil in deep dermis, duct in dermis, pore at surface
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