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Upper GI
bleeding (Definitions (Upper GIT
Mouth to duodenum,…
Upper GI
bleeding
Definitions
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Fresh PR bleed
Fresh blood PR, usually due to
lower GI bleed but can be from
a profuse upper GI bleed
Aetiology
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Vascular
Throat: oesophageal varices, Mallory-Weiss
Stomach: ulcers, erosions
Bowel: ulcers, angiodysplasia, aorto-enteric fistula
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Drugs
NSAIDs, aspirin
Steroids
Anticoagulants
Diagnosis
Examination
General
Pallor, fever, cachexia
Abdo
Pallor, kolinychia, mouth ulcers,
abdominal tenderness, signs liver disease
PR
Malaena, PR fesh blood, mass
Investigations
Bedside
Obs (shock, fever)
ECG (tachy, arrythmia)
Bloods
Group+save, crossmatch
FBC (anaemia, infection), CRP (infection),
U+E (high urea), LFTs (liver disease)
clotting (coagulation defect)
ABG, blood cultures (if infection)
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History
DH
NSAIDs, steroids, anticoagulants
FH
IBD, malignancy, coagulopathy
PMH
Previous bleeds, liver disease, IBD, malignancy
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PC/HPC
Haematemesis, malaena, PR bleed
Vomiting, dysphagia, fever, red flags
Risk scoring
Rockall
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Parameters
Pre: age, shock (SBP, HR), comorbidity
Post: diagnosis, signs of bleeding
Interpretation
Pre (max 7): 0=low risk; >6=surgery
Post (max 11): 0-1=low, 2-4=intermed; 5+=high
Glasgow-Blatchford
Parameters
Urea, Hb, SBP, HR,
symptoms (malaena, syncope),
comorb (liver disease, CCF)
Interpretation
6=likely need intervention
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Clinical
presentation
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Haematemesis
Fresh blood, coffee ground
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Pathophysiology
Can arise from pathology anywhere from
mouth, throat, stomach, upper small intestine
Haematemesis and/or malena, may have
fresh PR blood if large bleed
Management
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Definitive
TREAT CAUSE
Medical
Clotting
Indication: clotting derangement
E.g. platelets, FFP, vitamin K
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ADH agonist
Indication: suspected varices
MOA: ADH analogue, reduces BP
Surgical
Investigative endoscopy
Varices: banding, sclerotherapy, coagulation, TIPSS
Ulcers: haemostasis
Open surgery
Indication: severe bleeding, uncontrolled bleed
Conservative
Monitoring (obs, bloods)
Stop offending drugs