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Role of auxin in abscission (Biosynthesis (Trp-dependent pathway (Indole-3…
Role of auxin in abscission
Mechanism of action
Young leaves and fruits produced auxin
When level of auxin decreased, abscission layer formed at the base of petiole
Petiole broke and leaf fall to the ground
When level of auxin increased
Abscission of petiole was delayed
Petiole remained attach to the stem for few days
Structure
Derived from tryptophan
Six-sided carbon ring of tryptophan attached to five-sided ring containing carbon
Pathophysiology
In human, auxin is considered as uremic toxic derived in tryptophan metabolism
Involvement of auxin in human pathophysiology has not been further investigated
Auxin induces cell proliferation in an experimental model of mammalian renal tubular epithelial cells
Cell proliferation significantly increased as the auxin concentration increased.
LLC-PK1 cell line that is derived from the kidney of healthy male pig is used as the model of the experiment
A rapid colorimetric assay was used to determine the growth effects of auxin against LLC-PK1 cell lines
In human, this hormone can be used in kidney regeneration.
Functions of auxin
Plant growth and development
Control seedling orientation
Stimulate root branching
Stimulate shoot elongation
Promote fruit development
Receptors
Auxin-Binding Protein 1 (ABP 1)
Transport-Inhibitor Resistant 1 (TIR 1)
Induced acceleration of the degradation of the IAA1-luciferase
hybrid protein
Biosynthesis
Trp-dependent pathway
Indole-3-acetaldoxime (IAOX) pathway
Indole-3-acetamide (IAM) pathway
Tryptamine (TAM) pathway
Indole-3-pyruvic acid (IPA) pathway
Trp-independent pathway
