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Airway (Lower (alveoli (surrounded by vasculature for gas exchange to take…

- - - - wan to be collapsed
        
        surfactant keeps them open
        
        surfactant requires nitrogen (from room air)
        
        if on 100% O2, surfactant stops being produced over days
  - - - takes 150ml of air to get from mouth to the alveoli
        
        if I can't get more than 150ml, then i'm dead
        
        if increase O2 demand (exercise or illness) 350ml is not enough
        
        when O2 demand goes up, we breath faster and deeper. if body can't compensate then your sats drop, not getting the depth and not getting the ventilation needed for gas exchange
        
        woman 70 kg breaths 350 - 700 ml of air at rest
- - - - as CO2 climbs, chemo receptors stimulates you to breath more
        
        blow off CO2
  - - - stimulates you to breath more rapid and deeper
- - - - increased pressure from obesity or fluid
        
        not adequit ventilation
- - - - SATS saturation of Hgb
      - GI bleed hgb - 6
        
        sats 98
        
        PO2 70, not enough cars in hgb train to carry the O2
        
        O2 carrying capacity of the blood is how much Hbg do you have
        
        through diffusion, vent, perfusion we can get them saturated but it won't matter if not enough hgb to enough O2 to meet body demand
- - - - goes from aerobic to anaerobic metabollism, lactic acid is made, septic shock
        
        get acidotic from septic shock
        
        metabolic acidosis, end stage organ failure
  - - - goes from aerobic metabolism to anaerobic, lactic acid is made, septic shock,
        
        get acidotic from septic shoc
        
        metabolic acidosis end stage organ failure
- - - - should be warmed and humidified because bypassed those mechanisms
      - worried about swallowing
      - dysphasia issues
      - anaphylaxis
      - epiglotitis