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Endocrine Pharmacology, Concept Map Legend, Red Box Represents Core…
Endocrine Pharmacology
hormone types include
Peptide Hormones
are bound to
includes
Oxytocin
Insulin
decrease glucose level within blood by
promoting cell glucose uptake
cell unresponsive or unable to produce can lead to
Type 1 Diabetes
may cause
Ketoacidosis
Type 2 Diabetes
may cause
Hyperosmolar-Hyperglycemic State
is categorized into
Bolus Insulin
includes
Insulin Regular
Basal Insulin
includes
Insulin Glargin
Glucagon
increase glucose level within blood by
promoting conversion of glycogen to glucose
Tyrosine Derivative
Steroid Hormones
are bound to
includes
Cortisol
is an agonist to
Glucocorticoid Receptor
is produced by the body in
Flight or Fight Response
and increases
Blood Glucose Concentration
by
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Progesterone
is an agonist to
Progesterone Receptor
Estrogen
is an agonist to
Estrogen Receptors
production decreases as
Females Enter Menopause
which may cause
Osteoporosis
is a leading contributor to
10% of adults over 40 have osteoporosis (~1.5 million adults) in Canada
are bound to
often used by athletes are called
Anabolic Steroids
which increases
The Amount of Proteins Available for Muscle Repair
leading to
More Muscle Growth and Enhanced Athletic Performance
can cause many side effects including
Psychiatric Disorders, Decreased Sex Drive, Decreased Sperm Count, Decreased Testicular Size
which explains why
Some Athletes Experience "Roid Rage"
hormone receptor types include
Intracellular Receptor
Cell Surface Receptor
In circulation, some hormones are bound to
Carrier Proteins
treatment of endocrine disorders include
Hormone Replacement Therapy
can also be used to treat
Hypogonadism
which results in
The Insufficiency in Production of Sex Hormones
Intersex Conditions
that may include
Turner Syndrome
Klinefelter Syndrome
Radiation
Surgery to Remove Endocrine Gland or Tumor
this process may require the use of
Anesthetics
that includes
Opiate Agonists
like
Fentanyl
Morphine
Hydromorphone
controlling hormone release by
Feedback Regulation
negative feedback of glucocorticoid administration contributes to
endocrine cell examples
Beta Cells
secrete
Alpha Cells
secrete
3 categories of endocrine disorder
Secondary
is located
Up Stream
Tertiary
is located
Most Upstream
Primary
is located
Most Downstream
abrupt discontinue of exogenous hormones may cause
Temporary Atrophy of Adrenal Glands
also known as part of the
Farquharson Phenomenon
which is named after
Doctor Ray Farquharson
whom contributed to the formation of
Medical Research Council of Canada
which is the predecessor of
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can lead to
Insufficient Cortisol Production In Sympathetic Nervous System
characteristic of hormones
Hydrophobic or Hydrophilic
which affects
The Hormone's Ability to Permeate Cell Membrane
determines the hormone
hormones have different rate of breakdown depending on
whether the hormone is coupling with carrier proteins
hormones have different rate of response depending on
Receptor Location
Mechanism of Action
different hormone MOAs include
Steroids: Influence transcription of target genes
Peptides: Alter intracellular signal transduction pathways
Concept Map Legend
Red Box Represents Core Concepts From Endocrine Pharmacology Lecture
Green Represents Concepts From Other Lectures
Yellow Represents Real Life Concepts Or Practical Applications