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Protein - Coggle Diagram

- - - - actin, myosin in cardiac, skeletal, smooth muscle
    - - collagen, elastin, keratin: found in bone, teeth, skin, tendons, blood vessels, hair, nails
    - - spherical shape: myoblobin
  - - - proteins catalyzing reactions, some require cofactors
    - - -act as chemical messengers : eg. insulin, glucagon, catecholamines
        
        synthesized & secreted by endocrine glands
    - - In cell membrane - regulation of nutrient entry
        
        Uniporter
        
        Symporter - SGLT 1
        
        Antiporter - exchange molecules
      - In blood
        
        Hemoglobin
        
        albumin ( FA)
        
        prealbumin ( thyroxin & RBP)
        
        trasnferrin (iron)
        
        ceruloplasmin ( copper)
        
        lipoproteins
    - - Intra & extracellularly: help attract water = contributes to osmotic pressure
      - Ascites : abnormal accumulation of fluid in abdominal cavity --> anemia
  - - - formed in liver, in response to infection, inflammation
        
        -stimulate immune system, promote wound healing, chelate & remove free iron ( anti-bacterial)
      - C- reactive protein
        
        indicator for inflammatory status
    - - Glucose storage: glycogenin
    - - glycoprotein
- - - - α - helix ( cylindric shape)
      - β - pleated sheet
  - - - eg. linear, globular, spherical
      - eg. α - lactalbumin ( part of milk, impact lactose production in milk)
  - - - eg. Hemoglobin
- - - - Inborn error in metabolism: **missing phenylalanine hydroxylase ( cant convert to tryosine - become essential AA)