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OSTEOGENESIS IMPERFECTA osteogenesis imperfecta - Coggle Diagram
OSTEOGENESIS IMPERFECTA 
DEFINITION
A group of inherited disorders characterized by fragile bones that break easily (Heidari B, 2011).
CLINICAL MANIFESTATION
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• multiple broken bones (Heidari B, 2011).
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COMPLICATION
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• Respiratory problems and pneumonias due to chest wall deformities (Heidari B, 2011)..
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DIAGNOSTIC TEST
• a complete medical history and physical exam (Guo, Q., Wang, Y., Xu, D.,2018)
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PATHOPHYSIOLOGY
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• These genes affect how the body makes collagen, a protein that helps strengthen bones.
• The condition can be mild, with only a few fractures during a person's lifetime.
• In more severe cases, it can involve hundreds of fractures that occur without any apparent cause. (Guo, Q., Wang, Y., Xu, D.,2018)