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alcohol and viral hepatitis - Coggle Diagram
alcohol and viral hepatitis
Chronic inflamation
Damage hepatocytes
activate stellate cells
Deposite collagen in perisinosidal space
Scaring and fibrosis
Compress sinosoids
Portal HTN
Fluid leak into intestestial space
Ascitis
Ankle swelling
Blood backs up into spleen because not able to enter the liver
Spelenomegaly
Decrease production of albumin
Hypoalbuminemia
Lead to
Hepatocytes not able to conjugate bilirubin so HIGH UBR in blood
Jaundice
Bile leaks into blood which contain CBR into blood
urobiligion in urine analysis and dark urine
Less bile to intestine
Fat malabsorption and less fat soluble vitamin absorption
Fatigue
Low clotting factors
High INR and PT
HbsAG +
Acute or chronic
In our case, more than 2 yrs chronic
HBeAG+
Virus is replicating
HBeAB -
Not resolved
HBV DNA +
Virus is replicating
HIGH ALP
High GGT
AST higher than ALT ( both high)
Low platelet is direct toxic effect of alcohol