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Hematoimmunology System, Features of Determinants, Social Determinants -…

- - - - Physiology
        
        Hematopoiesis
        
        Hemostasis
        
        Transporting oxygen
        
        Defense against foreign invasion
        
        Fat production
      - Anatomy
        
        Found within the spongy or cancellous portions of bones
        
        Hips
        
        Breastbone
        
        Ribs
        
        Skull
        
        The ends of long bones (arms and legs)
      - Histology
        
        Bone Marrow Constituents
        
        Stroma
        
        Hemopoietic Cords
        
        Sinusoidal Capillaries
        
        Bone Marrow Matrix
        
        Type I Collagen
        
        Proteoglycan
        
        Fibronectin
        
        Laminin
  - - - Granulocytes
        
        Neutrophil
        
        Eosinophil
        
        Basophil
      - Agranulocyte
        
        Monocyte
        
        Macrophage type 1
        
        Macrophage type 2
        
        Lymphocyte
        
        B Lymphocyte
        
        T Lymphocyte
  - - - Phases
        
        Progenitor
        
        BFU (Burst-Forming Unit-Erythroid)
        
        CFU (Colony-Forming Unit-Erythroid)
        
        Precursor
        
        Pronormoblast
      - Stages of Erythrocyte Maturation
        
        Proerythroblast
        
        Basophilic Erythroblast
        
        Polychromatophilic Erythoblast
        
        Orthohromatophilic Erythroblast (Normoblast)
        
        Late Normoblast
        
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    - - Stem Cells
        
        Myeloid
        
        Myeloblast
        
        Pro myeloblast
        
        Myelocyte
        
        Band cell
        
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        Megacaryoblast
        
        Pro Megacaryoblast
        
        Megacaryocyte
        
        Platelets
        
        Lymphoid
        
        Lymphoblast
        
        Prolymphocyte
        
        Lymphocyte
        
        B Lymphocyte
        
        T Lymphocyte
  - - - Anemia
        
        Hypoproliferative Anemia
        
        Aplastic Anemia
        
        Myelophthisic Anemia
        
        Chronic Inflammation Anemia
        
        Iron Deficiency Anemia
        
        Megaloblastic Anemia
        
        B12 Deficiency Anemia
        
        Folate Deficiency Anemia
        
        Hemolitic Anemia
        
        Hereditary Spherocytes
        
        Sickle Cell Anemia
        
        G6PD Deficiency Anemia
        
        Acute Blood Loss Anemia
      - Thalassemia
        
        Alpha Thalassemia
        
        Silent Carrier
        
        Alpha Thalassemia Trait
        
        Non-Transfussion Dependent (NTDT)
        
        Transfussion Dependent (TDT)
        
        HbH Disease
        
        Alpha Thalassemia Major
        
        Beta Thalassemia
        
        Beta Thalassemia Trait
        
        Beta Thalassemia Intermedia
        
        Beta Thalassemia Major
    - - Proliferative Disorders
        
        Reactive
        
        Neoplastic
      - Leukopenia
        
        Lymphopenia
      - Leukemia
        
        Acute Myeloid Leukemia (AML)
        
        Chronic Myeloid Leukemia (CML)
        
        Acute Lymhoid Leukemia (ALL)
        
        Chronic Lymphoid Leukemia (CLL)
      - Granulocytosis
      - Agranulocytosis
      - Neutropenia
        
        Autoimmune Neutropenia
    - - Thrombotic Thrombocytopenic Purpura
      - Thrombocytopenia
      - Thrombocytosis
      - Von Willbrand Disease
      - Haemolitic Uremic Syndrome
    - - Multiple Myeloma
      - Waldenstorm's Macroglobulinemia
      - POEMS Syndrome
        
        Polyneuropathy
        
        Organomegaly
        
        Endocrinopathy
        
        M Proteins
        
        Skin Changes
      - Amyloidosis
        
        AL Amyloidosis
        
        AA Amyloidosis
        
        ATTR Amyloidosis
  - - - Polyarcrylamide Gel Electrophoresis
      - Giemsa Staining
      - Wright Staining
- - - - Thymus
        
        Anatomy
        
        Location
        
        Superior mediastinum and anterior of the inferior mediastinum, close to the pericardium
        
        The two distinct lobes of the thymus are connected in the midline by an isthmus
        
        Blood Supply
        
        From the internal thoracic artery
        
        From the superior and inferior thyroid arteries
        
        Drainage to the left innominate vein, superior, middle, and inferior thyroid veins
        
        Lymphatic Supply
        
        Drainage to the thymic lymph nodes
        
        Nerve Supply
        
        Arises form vagus nerves and sympathetic nervous system
        
        Physiology
        
        Maturation of T cells
        
        Defense against foreign invasion
        
        Histology
        
        Capsule
        
        Septa
        
        Medulla
        
        Cortex
        
        Adipose tissue
        
        Thymic epithelial cells
        
        Hassall corpuscles
      - Bone Marrow
        
        Red Bone Marrow
        
        Yellow Bone Marrow
    - - Spleen
        
        Anatomy
        
        Location
        
        Anteriorly, the stomach
        
        Posteriorly, the left part of the diaphragm, which separates it from the pleura, lungs, and ribs 9-11
        
        Inferiorly, the left colic flexure
        
        Medially, the left kidney
        
        Parts of Spleen
        
        The Extremist
        
        Anterior Extremity
        
        Posterior Extremity
        
        The Borders
        
        Margo Superior
        
        Margo Inferior
        
        The Surfaces
        
        Diaphragmatic Surface
        
        Visceral Surface
        
        Dimention
        
        Odd number size
        
        1 inch thick
        
        3 inches wide
        
        5 inches long
        
        weight 7 ounces
        
        Blood Circulation
        
        Arterial Splenica
        
        Arterial Trabecular
        
        Central Arteriole
        
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        Physiology
        
        RBC filters
        
        Immune System
        
        Stores Platelets
        
        Recycle Iron
        
        Histology
        
        Capsule
        
        Trabeculae
        
        Trabecular Vein
        
        Trabecular Artery
        
        White pulp
        
        Periarerioral Lymphoid Sheath
        
        Marginal Zone
        
        Lymphoid Follicles
        
        Red pulp
        
        Splenic Cords
        
        Venous Sinuses
        
        Central Artery
        
        Germinal Center
        
        Pulp Arteries
      - Liver
        
        Anatomy
        
        Location
        
        The right hypochondrium and epigastric areas, and extends into the left hypochondrium
        
        Liver Surfaces
        
        Diaphragmatic Surface
        
        Visceral Surface
        
        Liver Ligaments
        
        Falciform Ligaments
        
        Coronary Ligamen
        
        Triangular Ligaments
        
        The left triangular ligament
        
        The right triangular ligament
        
        Lesser Omentum
        
        Hepatic Recesses
        
        Subphrenic Spaces
        
        Subhepatic Space
        
        Morison's Pouch
        
        Anatomical Structure
        
        Macroscopic
        
        Glisson's Capsule
        
        Falciform Ligaments
        
        Caudate Lobe
        
        Quadrate Lobe
        
        Porta Hepatis
        
        Microscopic
        
        Lobules
        
        Central Vein
        
        Arteriole
        
        Venule
        
        Bile Duct
        
        Lymphatic Vessels
        
        Vagus Nerve
        
        Blood Supply
        
        Hepatic Artery Proper (25%)
        
        Vein and artery
        
        Central Vein
        
        1 more item...
        
        Hepatic Portal Vein (75%)
        
        Nerve Supply
        
        Hepatic Plexus
        
        Porta Hepatis
        
        Lower intercostal nerves
        
        Lymphatic Drainage
        
        Hepatic Lymph Node
        
        Phrenic and posterior mediastinal nodes
        
        Physiology
        
        Blood synthesis and secretion of plasma protein
        
        Detoxification
        
        Storage of glucose
        
        Glucogenesis
        
        Amino acid deamination
        
        Storage of vitamin A
        
        Removal of effete erythrocytes
        
        Storage of iron in complexes with the protein ferritin
        
        Histology
        
        Hepatocytes
        
        Smooth Endoplasmic Reticulum (SER)
        
        Mitochondria
        
        Golgi Network
        
        Peroxisomes
        
        Glycogen Deposits
        
        Lipid Droplets
        
        Lysosomes
        
        Sinusoids
        
        Parenchyma
        
        Space of disease
        
        Stroma
        
        Kupffer Cells
        
        Endhotelial Cells
        
        Stellate Cells
      - Tonsils
        
        Anatomy
        
        Blood supply
        
        Lingual tonsils
        
        From the lingual artery
        
        Pharyngeal tonsils
        
        From palatine artery
        
        Palatine tonsils
        
        From the tonsillar artery branches
        
        Location
        
        Pharyngeal tonsils
        
        In the posterior part of the tongue base
        
        Palatine tonsils
        
        Between palatoglossal arch interiorly & palatopharyngeal arch posteriorly
        
        Lingual tonsils
        
        In the superior part of the nasopharynx
        
        Covering capsule
        
        Pharyngeal tonsils
        
        Single crypts
        
        Palatine tonsils
        
        No crypts
        
        Lingual tonsils
        
        15-20 crypts
        
        Physiology
        
        Providing local immunity
        
        Providing surveillance mechanism
        
        Histology
        
        Lymphoid nodule
        
        Crypts
        
        Connective tissue capsule
        
        Ephithelium
        
        Germinal center
      - Peyer Patches
        
        Anatomy
        
        In the mucus membrane on small intestines
        
        Histology
        
        Enterocytes
        
        Brush borders
        
        Dendritic cells
        
        Lymphoid nodules
        
        Vili
        
        L & B lymphocytes
        
        Basement membrane
        
        Physiology
        
        Immune surveillance of materials in digestive system
      - Lymphatic System
        
        Anatomy
        
        Lymph fluid
        
        Interstitial fluid
        
        Lymphatic capillaries
        
        Composed by endothelial cells
        
        Found along the capillary network
        
        Lymphatic vessels
        
        Lymphatic valve
        
        Lymph ducts
        
        Right lymphatic duct
        
        Subclavian veins
        
        Thoracic duct
        
        Lymph trunk
        
        Lumbar trunks
        
        Legs, pelvis, kidneys, adrenal glands, abdominal walls
        
        Intestinal trunks
        
        Stomach, intestine, pancreas, spleen, part of liver
        
        Bronchomediastinal trunk
        
        Thoracic wall, lungs, heart
        
        Subclavian trunk
        
        Hands
        
        Jungular trunk
        
        Head and neck
        
        Lymph Circulation
        
        Lymph
        
        Lymph capillary
        
        Afferent lymph vessel
        
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        Lymph node
        
        Cervical (Neck) Lymph Nodes
        
        Axillary (Armpit) Lymph Nodes
        
        Supraclavicular Lymph Nodes
        
        Mediastinal Lymph Nodes
        
        Inguinal (Groin) Lymph Nodes
        
        Retroperitoneal Lymph Nodes
        
        Mesenteric Lymph Nodes
        
        Pelvic Lymph Nodes
        
        Physiology
        
        Returns fluid
        
        Returns large molecules
        
        Absorb and transport fats
        
        Hemopoiesis
        
        Body defense/immunity
        
        Histology
        
        Capsule
        
        Trabeculae
        
        Cortex
        
        Lymphoid follicles
        
        Lymphatic nodules
        
        Germinal center
        
        Follicular dendritic cells
        
        Paracortex
        
        T cells
        
        Dendritic cell
        
        Medulla
        
        Medullary cords
        
        Medullary sinuses
  - - - Thymic Hyperplasia
      - Thymomas
    - - Splenomegaly
        
        Nonspesific acute splenitis
        
        Congestive splenomegaly
        
        Splenic infarcts
      - Neoplasm
      - Lympadenitis
      - Congenital anomalies
      - Rupture
    - - Lymphadenitis
        
        Acute non-specific lymphadenitis
        
        Hemaophagocytic lymphohistiocytosis
        
        Chronic non-specific lymphadenitis
      - Lymphoma
        
        Hodgkins Lymphoma
        
        Non-Hodgkins Lymphoma
    - - Hypersensitivity
        
        Hypersensitivity type 1
        
        Hypersensitivity type 2
        
        Hypersensitivity type 3
        
        Hypersensitivity type 4
      - Autoimmune Disease
        
        Immunodeficiency
        
        Primary Immunodeficiency Disease
        
        PID defects in complement system
        
        PID defects in lymphocyte
        
        X-linked agammaglobulinemia
        
        Severe combined
        
        X-linked SCID
        
        Autosomal recessive SCID
        
        Digeorge syndrome
        
        Immunodeficiency associated with systemic disease
        
        Wiskott-Aldrich Syndrome
        
        Ataxia telangiectasia
        
        Common variable immunodeficiency
        
        PID defects in leukocytes
        
        Leukocyte adhesion deficiencies
        
        Chronic granulomatous disease
        
        Chediak-higashi syndrome
        
        TLR defects
        
        Secondary Immunodeficiency Desease
        
        Acquired Immunodeficiency Syndrome
        
        Irradiation & cancer chemotherapy
        
        Involvement of bone marrow cancer
        
        Protein calorie malnutrition
        
        Removal of spleen
        
        Hyper Immuno Disease
        
        Systemic Lupus Erythromatosus
        
        Chronic Discoid Lupus
- - - - Complex Behaviour
      - Simple or Discrete Behaviour
  - - - Etiological Phase
        
        Social and Environmental Determinants
        
        Risk and Protective Factors
      - Preclinical Phase
      - Clinical Phase
      - Post-clinical Phase
      - Prevention
        
        Primordial
        
        Primary
        
        Tertiary
        
        Secondary
      - Reciprocal Determinism
  - - - Social Construct
        
        Gender
        
        Differential occupational experiences
        
        Marital experiences
        
        Degree of emancipation for women
        
        Effect
        
        Political circumstances
        
        Social circumstances
        
        Economic circumstances
  - - - Individual
      - Socioeconomic
      - Sociocultural
      - Environmental
      - Otawa Charter
        
        Build health public policy
        
        Create supportive environments for health
        
        Strengthen community action for health
        
        Develop personal skills
        
        Reorient health services
    - - Health Education
        
        Tones
        
        Respect
        
        Empathy
        
        Genuine
        
        Helath Promoters
        
        Friere's model
    - - Quantitative Assessment
        
        Estimating risk magnitude
        
        Participants
        
        Judgement modes
        
        More frequent
        
        Number of deaths
        
        Results
        
        Relative and absolute risks
        
        Evaluative standards
        
        Consistency
        
        Accuracy
        
        Probability judgements
        
        Defining risk
        
        Death and other outcomes
        
        Catastrophic potential
        
        Dimensions of risks
        
        Risk comparison
      - Qualitative Assessment
        
        Supplying Details
        
        Cumulative Risk
        
        Mental Modes
        
        Risk Decision
        
        Take Ride
        
        Accident (p1)
        
        Arrive Safely (1-p1)
        
        Decline Ride
        
        Be Understood (p2)
        
        Be Criticized (1-p2)
        
        Possible Consequences
        
        Impact on health
        
        Impact on image
        
        Dollar cost
        
        Enjoyment
  - - - Selecting content
      - Identifying the most relevant
      - Begin with facts
      - Focus on the information
    - - Clear structure
      - Clear hierarchy of information
      - Readers receive adjunct aids
    - - The information that recipients need
      - Afford them access to information
      - Allows them to comprehend the information
    - - Subject matter specialist
      - Risk and decision analysts
      - Behavioural scientist
      - Communication practitioners
  - - - Ageing and Urbanization
      - Health Risk and Benefits of Urbanization
- - - - Anticlotting Drugs
        
        Antiplatelets Drugs
        
        Cox inhibitors
        
        Aspirin
        
        P2Y12 receptor blockers
        
        Irreversible
        
        Ticopidine
        
        Clopidogrel
        
        Prasugrel
        
        Reversible
        
        Ticagrelor
        
        Cangrelor
        
        GP IIb IIIa inhibitors
        
        Monocloal antibody
        
        Abciximab
        
        Synthetic molecules
        
        Empifibatide
        
        Tirofiban
        
        Phophodiesterase inhibitors
        
        Dipyridamole
        
        Cilostazol
        
        Thrombolytics
        
        t-PA derivatives
        
        Streptokinase
        
        Anticoagulants
        
        Heparins
        
        Direct thrombin inhibitors
        
        Warfarin
      - Clotting-Facilitated Drugs
        
        Antiplasmin drugs
        
        Vitamin K
        
        Replacement factors
    - - Microtubule Inhibitor
      - Antitumor Antibiotic
      - Alkylating Agents
      - Antimetabolite Agents
      - Topoisomeracy Inhibitor
  - - - Cytokines inhibitor
        
        IL-2
        
        IL-1
        
        IFN-alpha
        
        IFN-beta
        
        IL-15
        
        IL-22
    - - Cytotoxic agent
      - Calcineurin Inhibitor
      - Corticosteroid
      - Mtor Inhibitor
      - Monoclonal antibodies
      - Immunosuppressive antibodies