Blood System

Order:

Heart

Arteries

Tissues (capillaries)

Veins

Back to heart

Detailed Order:

Heart

Large Artery

Medium Artery

Small Artery

Arteriole

Capillary

Venule

Small Vein

Medium Vein

Large Vein

Back to Heart

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Arteries

Arteries are blood vessels that take blood away from the heart

As arteries become more distant from the heart, their diameter decreases

Thinnest artery:

Arteriole

Branches off into a capillary bed

(a net of capillaries)

Is is the level of capillaries that all exchanges of nutrients and waste between the blood and body cells occur

The capillary bed then merges into venules

(thinnest veins)

Which merge into thicker and thicker veins until they reach the heart

Veins

Are blood vessels that bring blood into the heart

Take blood at high pressure away from the heart to the tissues of the body

Their walls are thick with elastic and muscle tissue that work with the heart to facilitate and controle blood flow

The elastic fibers stretch and recoil

helping propel the blood down the artery

The contraction of smooth muscle in the walls of arteries determines the diameter of the lumen and the rigidity of arteries

The aorta and the pulmonary artery take blood from the left and right ventricles, respectively

Bring blood at low pressure back to the heart

Their walls are thin with little elastic and muscle tissue

Veins have internal valves that close when blood start flowing backwards, preventing this back flow

The pulmonary vein and the vena cava bring blood to the left and right atria, respectively

The Human Heart

Capillaries

Allow exchanges between body tissues and blood to occur

Their walls are one cell thick only

with no elastic and muscle tissue

Cells that form the wall of capillaries are called endothelial cells

In most capillaries, there are pores between the endothelial cells

which allows some plasma to leak from the bloodstream into tissues

The permeability of capillaries varies among organ to organ

The diameter of capillaries is of about 10 um.

The net of capillaries in a tissue is often referred to as a capillary bed

Cartilages, the cornea and the eye lens do not have capillaries

Blood Vessels

Pulmonary Circulation

Takes blood from the heart (right side) to the lungs and back

Systemic Circulation

Takes blood from the heart (left side) to the body, except for the lungs

Coronary arteries:

Supply the heart muscle with oxygen and nutrients

Control of heart Rate:

Cardiac muscle cells are able to contract without nervous stimulation

(myogenic)

But their contraction must be synchronized

in order for the heart muscle to pump blood effectively

This synchronization is achieved through the activity of a natural pacemaker

the sinoatrial node (SA node)

its cells are the first to depolarize. It sends out an electrical signal that stimulates contraction of both atria

it also sends a signal to the atrioventricular node (AV node) to make it send its signal

AV node: sends electrical signals to trigger the contraction of both ventricles

Nervous and Endocrine Stimulation

The heart is able to contract autonomously

but it receives stimulation from the central nervous system (CNS)

either directly (through nerves) or indirectly (through hormones) to pump blood according to the body's needs

Receptors in blood vessels send information to the CNS about blood pressure, pH, and oxygen concentration

Low blood pressure, oxygen, and pH causes an increase in the heart rate

High blood pressure, oxygen and ph cause the heart rate to slow down

Epinephrine (Adrenaline)

Hormone that increases the heart rate

released in situations of stress to prepare the animal for a fight-or-flight response

Cardiac Cycle

Sequence of events that repeat every heartbeat

Divided into

systole (contraction)

diastole (relaxation)

1.

Starts with signal generation in the SA node

a) atria contract --> increase in pressure inside atria

2.

AV node sends signals to the ventricles

a) ventricles contract (ventricular systole)

  • increase in pressure inside venricles
  • atrioventricular valves close (1st heart sound)
  • Rapid increase in pressure inside ventricles

b) semilunar valves open

  • increase of pressure inside aorta

(equals pressure inside ventricles)

c) semilunar valves close (2nd heart sound)

  • end of systole/beginning of diastole

d) atrioventricular valves open

  • pressure inside atria drops as blood flows to ventricles