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Summer Project MEngSc Biopharmaceutical Engineering Robotics in fill…
Summer Project MEngSc Biopharmaceutical Engineering
Robotics in fill finish AAV Facility design
The integration of robotics into Aseptic Filling
goal to elimminate human intervention
operatives introduce contamination into the enviroment
Human are only required for intervention
Remote working Future
virtual interaction VR
how can this be done without loss of dexterity ?
Fully closed facility
GMP and regulatory concers/requiremnets
Designing smaller filling footprints
Removing RABS
The room becomes the RABS
removing the operator from the physical facility reduces the overall risk of contamination and human error through interaction
"Filler in a box" concept
Hybrid autonomous systems operated through the virtual reality enviroment.
Closed Isolators
Gloveless isolators
VANRX
Performing very specific tasks
the transformation from open to closed enviroments
Plug and Play
Lights out facility
Robots and co bots
Increase capacity through scalibility
the transformation from 20000 VPH to a number of small modular units working together
Market Drivers
Keeping humans away from the product
The ability to perform a rapid changeover from 1 to 5 to 10ml Vials to a syringe and cartridge extremeley efficiently compared to exsiting processes
2 Key Market Drivers
Summer Research Project
Current State of fill finish
Future for filll finish
QA In fill Finish
AAV Added to literature review important part of project story