Please enable JavaScript.
Coggle requires JavaScript to display documents.
Trisomy 13 & Trisomy 18 - Coggle Diagram
Trisomy 13 & Trisomy 18
-
Results in a mix of birth defects; severe cognitive and health problems which affect almost all organs.
Most likely results in death at age 1, though a few have been reported to survive until their teens.
-
Cause:
While the 46 chromosomes are being divided in half, errors, in which extra copies of chromosomes - in this case no. 13 and no. 18 - are made, may occur.
Sometimes, a translocation may happen, which is when an extra copy of no. 13 and 18 or part of it is attached to another chromosome within the egg or sperm. Only this form of trisomy 13 or 18 can be inherited by the offspring from their parents. Balanced translocation, in which chromosome 13 or 18 is attached to another chromosome, doesn't affect the offspring's health.
Mosaic trisomy 13 or 18 is a rare form of these disorders. This is caused by a post-fertilization error in dividing the cells. Those with this disorder have both normal cells and ones with extra copies of no. 13 or 18.
Trisomy 13
Symptoms
Low-set, unusual-shaped ears
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
Diagnosis
Checking the cells in the amniotic fluid or from the placenta and/or checking the amount of the baby's DNA in the mother's blood. These methods involve non-invasive prenatal screening and are highly accurate.
Ultrasound during pregnancy, though it's not 100% accurate.
-
Treatment for these disorder depends on the child's symptoms, age, general health, and symptom severity.