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Erythropoietic protoporphyria - Coggle Diagram
Erythropoietic protoporphyria
Signs and symptoms
Hypersensitive to sunlight
Burn tingle
Blister
Risk factors
Excess iron in body
Sun exposure
Certain drugs
Family history
Definition
Inherited disorder of ham metabolic pathway
Causes
Gene GATA1
Metabolic disorders
Gene mutation
Inborn errors of heam biosynthesis
Diagnostic test
Blood test
Gene test
Physical examination
Nursing care
Avoid known triggers
Prevent skin lesions
pathophysiology
Deposition of protoporphyrin crystals in hepatocytes and bile canaliculi
Accumulation of protoporphyrin molecules in the body
Loss of function mutation in ferrochelatase(FECH) gene.
Accumulation lead to high absorption of heat energy