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Puberty, นางสาวปวีณา หมื่อโป เลขที่ 51 รหัสนักศึกษา 622401051 - Coggle…

- - - - Prolactin
      - Thyroid function tests
      - Gonadotropins
      - Gonadal steroids
- - - - GA 20 weeks: peak of LH & FSH
      - At birth: LH & FSH concentrations are still high, then decline during 1st several week of life and remain low during the prepubertal years
      - GA 10 wk:GnRH is present in the hypothalamus and LH & FSH are present in the pituitary gland
    - - During childhood: hypothalamus is extremely sensitive to the negative feedback
      - As puberty approaches:subsequently increase the pulsatile GnRH secretion
      - The anterior pituitary responds by progressive secretion of FSH and LH associated with increased secretion of growth hormone
      - Causes development - the secondary sexual characters
      - Increased estrogen secretion: menarche and cyclic estrogen secretion occurs
      - Ovary
        
        E1 : estrone (+ fat)
        
        E2 : estradiol *most
        
        E3 : estriol
      - Adrenal gland
        
        androgen (ADD, DHA, DHAS) ↑
        
        Stimulating adrenarche: pubic & axillary hair
        
        2 years before the increases in gonadotropin & gonadal sex steroid secretion
  - - - Breast budding -- usually 1st recognized pubertal change (thelarche)
      - Secondary sex characters include: development of the
        breast, appearance of pubic and axillary hair
      - 1st sign -- accelerated growth (growth spurt)
    - - เริ่มพัฒนาเต้านม
      - เริ่มพัฒนาขนหัวหน่าว
      - อัตราการโตสูงสุด
      - Maximal growth
      - ระดูครั้งแรก
      - ขนหัวหน่าวแบบผู้ใหญ่
      - เต้านมแบบผู้ใหญ่
    - - During the growth spurt, the long bones in the body lengthen, and the epiphyses ultimately close
      - Men have 1.5 times the lean body mass & skeletal mass of women
      - Girls reach peak height velocity early in puberty before menarche
      - Women have twice as much body fat as men
    - - Vagina
        
        Epithelium: thick, stratified squamous, containing glycogen
        
        length: increase, appearance of the rugae
        
        pH: acidic
      - Mons pubis, labia majora & minora: increase in size
      - Uterus
        
        Uterus:Cervix = 2:1
        
        enlarge
      - Ovaries
        
        Increase in size
        
        respond to the increase Gonadotropin secretion
        
        menarche: 300 thousands primary follicle
        
        almond shape