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Metabolism - Coggle Diagram
Metabolism
Enzymes lower the activation energy of the chemical reactions that they catalyze
Globular proteins
speed up chemical reactions lowering the activation energy
transform one type of energy into a more usable type of energy
Distinguishing different types of inhibition from
graphs at specified substrate concentration.
the substrate will have fewer encounters with the active site and rate of chemical reaction will be decreased
Temperature, pH, and substrate concentration affect the rate
of activity of enzymes.
Enzyme inhibitors can be competitive or non-
competitive.
non competitive: bind at a location other than the active site
Competitive:interfere with the active site so that the substrate cannot bind
End-product inhibition of the pathway that
converts threonine to isoleucine.
happens is a series of 5 enzyme catalyzed steps
isoleucine acts as a non-competitive inhibitor to threonine deaminase
Metabolic Pathways can be controlled by end product inhibition
End product: prevents the cell from wasting chemical resources and energy by making more of a substance that it needs
Use of databases to identify potential new anti-
malarial drugs.
Malaria is a disease caused by pathogen plasmodium falciparum.
Metabolic pathways consist of chains and
cycles of enzyme-catalyzed reactions.
the results of the reactions controlled often act to inhibit further enzyme production, in a complex web of reactions