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Factors Affecting Glomerular Filtration Rate - Coggle Diagram
Factors Affecting Glomerular Filtration Rate
Filtration coefficient (Kf).
Increased Kf
raises GFR
decreased Kf
reduces GFR.
Hydrostatic pressure in bowman’s space fluid (PBS)
Opposes filtration,
therefore GFR is inversely related to it.
It is
incrd in acute obstruction of urinary tract
(e.g. a ureteric obstruction by stone).
Glomerular capillary hydrostatic pressure (PGC).
GFR is directly related to PGC.
Changes in PGC serve as a primary means
for physiological regulation of GFR.
PGC is mainly dependent on
arterial pressure,
renal blood flow,
afferent arteriolar resistance and
efferent arteriolar resistance.
4.Glomerular capillary oncotic pressure (πGC).
GFR is inversely proportional to πGC.
In hyperproteinaemia and in
haemoconcentration ratio,
the πGC is raised
leading to decrease in GFR.
Conversely,
in hypoproteinaemia and
haemodilution
the πGC is reduced
leading to increased GFR.