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Guillain-Barré Syndrome - Coggle Diagram

- - - - Most common in Europe and North America
      - Myelin sheath is damaged
    - - Most common in Asia
    - - Most common in China, Japan, and Mexico
      - Antecedent infection triggers an immune response that deposits antibodies and complements on peripheral nerve axons which leads to attachment of macrophages and eventually axonal collapse (Molecular mimicry)
    - - Most common in China, Japan, and Mexico
      - Same molecular mimicry as AMAN but more severe and ends in full axonal degeneration
- - - - Blood is temporarily removed from a patient's body and is filtered through a machine that removes abnormal antibodies. Blood is then returned to the patient's body with blood donor's albumin or plasma.
    - - Immunoglobulins are infused through an IV line into the patient's veins. Uses a mixture of antibodies to help fight the patient's antibody deficiency.
  - - - Used to monitor patient's heart if blood pressure is rising and falling
    - - Used if a patient is having trouble breathing on their own. Can be removed from the machine when they are able to breathe by themselves again.
    - - Used before and during treatment to keep muscles flexible and strong and to cope with fatigue and help the patient regain strength and proper movement. May also include training with a wheelchair or braces to give the patient mobility and more advanced self care skills.
    - - No specific medications used in the treatment of Guillain-Barré Syndrome. Patient's are mostly prescribed analgesics to help fight the pain and anticoagulants to help prevent blood clots from forming due to immobility of the patient.