Variant PMDs Not Meeting Criteria for Core PMDs
1. Premenstrual exacerbation of underlying disorder: E.g.: Diabetes, depression, epilepsy, asthma, and migraine. These patients experience symptoms relevant to their disorder throughout the menstrual cycle.
2. Non-ovulatory PMDs: Occur in the presence of ovarian activity without ovulation. Follicular activity of the ovary is thought to instigate symptoms.
3. Progestogen-induced PMDs: Caused by exogenous progestogens present in HRT and the COCP. This reintroduces symptoms to women who may be particularly sensitive to progestogens. Although progestogen-only contraceptives may introduce symptoms, as they are non-cyclical they are not included within variant PMDs and are considered adverse effects of continuous progestogen therapy.
4. PMDs with absent menstruation: Include women who still have a functioning ovarian cycle, but for reasons such as hysterectomy, endometrial ablation or the LNG-IUS, they do not menstruate.