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GANGRENE - Coggle Diagram

- - - - distal part of a limb due to ischaemia.
        
        other causes
        
        Raynaud’s disease,
        
        thromboangiitis obliterans
        ( Buerger’s disease)
        
        trauma
        
        Grossly:
        dry, shrunken, dark black.
        
        Histologically:
        necrosis with line of separation
        consisting of inflammatory granulation tissue
    - - Usually occurs in moist tissue and organs : bowel, lung, mouth, cervix, vulva
        
        Examples:
        
        diabetic foot,
        
        bedsores (due to pressure)
        
        Blockage of both venous and arterial blood flow
        
        Affected part stuffed with blood
        (promotes bacteria growth)
        
        Toxic products of bacteria absorbed causing septicaemia
        
        Grossly:
        soft, swollen, putrid, rotten and dark.
        
        1 more item...
    - - Special type of Wet Gangrene
        caused by gas-forming Clostridia
        (Gram positive anaerobic bacteria)
        
        Gains entry through open,
        contaminated wounds (muscles)
        
        Grossly:
        swollen, oedematous, painful, crepitant (gas bubbles of CO2: fermentation of sugars),
        dark black and foul smelling
        
        Microspcopically:
        
        coagulative necrosis and liquefaction.
        
        Gram positive bacteria,
        
        leucocytic infiltration,
        
        oedema and congestion
        
        table