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Pain, Suffering and Distress - Coggle Diagram
Pain, Suffering and Distress
Pain
"An aversive sensory experience representing awareness by the animal of damage or threat to the integrity of its tissues. It changes the animal´s physiology and behaviour to reduce the likelihood of its recurrence and to promote recovery. "
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Distress
"Distress occurs when the stress is of such magnitude or duration that significant changes in biological function must occur for the animal to survive" (Moberg, 2000)
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Physiological assssment
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And biochemical parameters e.g. acute phase proteins APP (fibrinogen, haptoglobin, serum mayloid) / plasma enzymes e.e. creatine kinase
or levels of bradykinin/ prostagladins, substance P for mastitis (a painful inflam conidition, neuro peptide BUT inconclusie results).
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Pain scoring
Assures scores are: sensitive, specific, and able to be reproducible
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Nerve/ skin / pleura next, blood vessle and viscera next and bones& joints next, last/ least sensitive =encephalic tissue
humane endpoint = can be defined as the earliest indicator in an animal experiment of (potential) pain or distress that, within the context of moral justification and scientific endpoints to be met, can be used to avoid or limit pain and/or distress by taking actions such as humane killing or terminating or alleviating the pain and distress.