Please enable JavaScript.
Coggle requires JavaScript to display documents.
Studies 1,2,4 - Coggle Diagram
Studies 1,2,4
S1Lifestyle Heart Trial, Ornish 2001
Results
5 year results
Intervention
7.9% REDUCTION IN STENOSIS (41 TO 37)
25 cardiac events total
Control (total)
27% INCREASE stenosis
45 cardiac events
Control (no statin)
47% INCREASE stenosis
More regression after 5 years than 1 year in intervention group
More adherance=more regression
48 Adults with CAD
Control n=20
Usual Care with statins
Usual Care no statins
(usual care= healthy eating and excercise)
Intervention n=28 (NO STATINS USED)
Low fat veg diet
aerobic excercise
smoking cessation
stress Mx
Group supporty
Design
CAD assessed with blinded angio at baseline, 1 & 5 years
35 pts completed
S2 Reduction in T2DM incidence- metformin vs lifestyle (KNOWLER)
3,234 patients with IFG
Primary outcome- incidence of T2DM
Participants
51 year mean age
BMI 34
67% women
45% minority groups
Results (2.8 Yrs)
Incidence T2DM/100 person years
placebo
11
Metfomrin
7.8
liftestyle
4.8
lifestyle red diabetes incidence by 58% compared to metformin (38%)
Goals of lifestyle programme
7% weight loss
150 mins acivity
S4: PCA VS excercise- pts with stable CAD Hambrecht (2004)
Study
compare excercise vs PCI for
symptoms
excercise capacity
myocardial perfusion
clinical end points
Death
cabg
stroke
angioplasty
hospitalization
101 male pts <70. Recuited after routine angio
Intervention
12 months excercise bike >20 mins to 70% symptom free HR
Conrol
PCI with stent
Results AT 1 YEAR
Event free survival
intervention/excercise
88%
PCI
70%
Cost
PCI
$6900
Excercise
$3429
Other positive outcomes
fewer revasculariozations
Fewer rehospitilizations
lower resting HR
impoved ischaemic threshold
INCREASED WORK CAPACITY
Increased v02 max
MORE COST EFFICIENT - Canadian cardiovascular society class 1
